Ethnobotanical Survey of Plants used in the Management of Sickle Cell Disease in Two Local Government Areas of Kwara State, North-Central Nigeria.
Bilqis A. Lawal and Jones O. Moody2

1Department of Pharmacognosy and Drug Development, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria. 2Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Ibadan Nigeria.
*Corresponding author: A. Lawal; Phone No:+2348033717230, Email: umufaridah2013@gmail.com,  lawal.ba@unilorin.edu.ng

ABSTRACT

Background: A lot of sufferers of sickle cell disease are left with physical disabilities, low self-esteem and confidence, little or no education and sometimes abject poverty. Medicinal plants have been a source of succour in the control of many diseases in developing countries and sickle cell disease is no exception. This study is aimed at carrying out an ethnobotanical survey for the purpose of documentation of plants used in the management of sickle cell disease (SCD) in one rural area (Irepodun Local Government) and one urban area (Ilorin-West Local Government) of Kwara State.

Methods: Interviews were conducted on plant species and remedies used in the management of sickle cell disease using semi-structured questionnaires and asking open-ended questions. The respondents (n = 40) were mostly traditional medical practitioners. Others were herb sellers, religious healers and patients. The Use Mention Index was calculated for all the plants mentioned both in single and multiple-species remedies; and the frequency and percentage was employed for data analysis.

Result: The ethnobotanical survey afforded a list of some plants used locally for the treatment of sickle cell disease by the people of Irepodun and Ilorin East Local Government Areas, Kwara State. A total of 57 plant species belonging to 34 families were identified. The most prominent among these plant families are the Fabaceae and Euphorbiaceae.

Conclusion: This study showed that Kwara State is blessed with abundant medicinal plant which can be a tool in the search for the management of sickle cell disease. Thus, research interest in medicinal plant as a potential source of new and reliable antisickling agent should be encouraged and adequately funded due to the fact that plants have been established as a reservoir of leads/hits chemical compounds in the drug discovery research.

Key words: Sickle cell disease, Medicinal plants, Ilorin-West Local Government, Irepodun Local Government, Kwara State.

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